Three sesquiterpene lactones suppress lung adenocarcinoma by blocking TMEM16A-mediated Ca(2+)-activated Cl(−) channels

Transmembrane protein TMEM16A, which encodes calcium-activated chloride channel has been implicated in tumorigenesis. Overexpression of TMEM16A is associated with poor prognosis and low overall survival in multiple cancers including lung adenocarcinoma, making it a promising biomarker and therapeuti...

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Detalles Bibliográficos
Autores principales: Xiu, Ruilian, Jia, Jie, Zhang, Qing, Liu, Fengjiao, Jia, Yaxin, Zhang, Yuanyuan, Song, Beibei, Liu, Xiaodan, Chen, Jingwei, Huang, Dongyang, Zhang, Fan, Ma, Juanjuan, Li, Honglin, Zhang, Xuan, Geng, Yunyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613571/
https://www.ncbi.nlm.nih.gov/pubmed/37884284
http://dx.doi.org/10.4196/kjpp.2023.27.6.521

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