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Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A(2A) receptors

Increasing evidence implicates astrocytic dysfunction in Alzheimer’s disease (AD), a neurodegenerative disorder characterised by progressive cognitive loss. The accumulation of amyloid-β (Aβ) plaques is a histopathological hallmark of AD and associated with increased astrocyte reactivity. In APP/PS1...

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Detalles Bibliográficos
Autores principales: Madeira, Daniela, Domingues, Joana, Lopes, Cátia R., Canas, Paula M., Cunha, Rodrigo A., Agostinho, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613596/
https://www.ncbi.nlm.nih.gov/pubmed/37898985
http://dx.doi.org/10.1007/s00018-023-04983-6