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Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A(2A) receptors
Increasing evidence implicates astrocytic dysfunction in Alzheimer’s disease (AD), a neurodegenerative disorder characterised by progressive cognitive loss. The accumulation of amyloid-β (Aβ) plaques is a histopathological hallmark of AD and associated with increased astrocyte reactivity. In APP/PS1...
Autores principales: | Madeira, Daniela, Domingues, Joana, Lopes, Cátia R., Canas, Paula M., Cunha, Rodrigo A., Agostinho, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613596/ https://www.ncbi.nlm.nih.gov/pubmed/37898985 http://dx.doi.org/10.1007/s00018-023-04983-6 |
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