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Tumor-suppressive microRNA-152 inhibits the proliferation of Ewing’s sarcoma cells by targeting CDK5R1

We elucidated the mechanism through which the reduced expression of miR-152 leads to the overexpression of its target cyclin-dependent kinase-5 activator 1 (CDK5R1) in Ewing’s sarcoma (ES) cells and the role of this mechanism in the proliferation of ES cells. To explore possible oncogenic factors in...

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Detalles Bibliográficos
Autores principales: Kawano, Masanori, Tanaka, Kazuhiro, Itonaga, Ichiro, Iwasaki, Tatsuya, Kubota, Yuta, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613623/
https://www.ncbi.nlm.nih.gov/pubmed/37899376
http://dx.doi.org/10.1038/s41598-023-45833-6

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