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Evaluating immunological and inflammatory changes of treatment-experienced people living with HIV switching from first-line triple cART regimens to DTG/3TC vs. B/F/TAF: the DEBATE trial

BACKGROUND: The aim of this randomized clinical trial (RCT) was to compare immunological changes in virally suppressed people living with HIV (PLWH) switching from a three-drug regimen (3DR) to a two-drug regimen (2DR). METHODS: An open-label, prospective RCT enrolling PLWH receiving a 3DR who switc...

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Detalles Bibliográficos
Autores principales: Cossarizza, Andrea, Cozzi-Lepri, Alessandro, Mattioli, Marco, Paolini, Annamaria, Neroni, Anita, De Biasi, Sara, Tartaro, Domenico Lo, Borella, Rebecca, Fidanza, Lucia, Gibellini, Lara, Beghetto, Barbara, Roncaglia, Enrica, Nardini, Giulia, Milic, Jovana, Menozzi, Marianna, Cuomo, Gianluca, Digaetano, Margherita, Orlando, Gabriella, Borghi, Vanni, Guaraldi, Giovanni, Mussini, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613634/
https://www.ncbi.nlm.nih.gov/pubmed/37908359
http://dx.doi.org/10.3389/fimmu.2023.1279390