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Gamma-secretase modulators: a promising route for the treatment of Alzheimer's disease

Recent clinical data with three therapeutic anti-Aβ antibodies have demonstrated that removal of Aβ-amyloid plaques in early Alzheimer's disease (AD) can attenuate disease progression. This ground-breaking progress in AD medicine has validated both the amyloid cascade hypothesis and Aβ-amyloid...

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Detalles Bibliográficos
Autores principales:	Nordvall, Gunnar, Lundkvist, Johan, Sandin, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613654/ https://www.ncbi.nlm.nih.gov/pubmed/37908487 http://dx.doi.org/10.3389/fnmol.2023.1279740

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