ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application

Estimating human exposure in the safety assessment of chemicals is crucial. Physiologically based kinetic (PBK) models which combine information on exposure, physiology, and chemical properties, describing the absorption, distribution, metabolism, and excretion (ADME) processes of a chemical, can be...

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Detalles Bibliográficos
Autores principales: Li, Hequn, Bunglawala, Fazila, Hewitt, Nicola J, Pendlington, Ruth, Cubberley, Richard, Nicol, Beate, Spriggs, Sandrine, Baltazar, Maria, Cable, Sophie, Dent, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Biotransformation, Toxicokinetics, and Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613959/
https://www.ncbi.nlm.nih.gov/pubmed/37584694
http://dx.doi.org/10.1093/toxsci/kfad081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613959/
https://www.ncbi.nlm.nih.gov/pubmed/37584694
http://dx.doi.org/10.1093/toxsci/kfad081

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