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Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions
Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality. While the genetics underlying many Mendelian diseases have been elucidated, it is harder to predict risk for complex diseases arising from the combined...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614359/ https://www.ncbi.nlm.nih.gov/pubmed/37904243 http://dx.doi.org/10.1186/s13073-023-01245-9 |