Landscape of enhancer disruption and functional screen in melanoma cells

BACKGROUND: The high mutation rate throughout the entire melanoma genome presents a major challenge in stratifying true driver events from the background mutations. Numerous recurrent non-coding alterations, such as those in enhancers, can shape tumor evolution, thereby emphasizing the importance in...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Luo, Menghan, Liang, Qian, Zhao, Ke, Hu, Yuelin, Wang, Wei, Feng, Xiangling, Hu, Bolang, Teng, Jianjin, You, Tianyi, Li, Ran, Bao, Zhengkai, Pan, Wenhao, Yang, Tielong, Zhang, Chao, Li, Ting, Dong, Xiaobao, Yi, Xianfu, Liu, Ben, Zhao, Li, Li, Miaoxin, Chen, Kexin, Song, Weihong, Yang, Jilong, Li, Mulin Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614365/
https://www.ncbi.nlm.nih.gov/pubmed/37904237
http://dx.doi.org/10.1186/s13059-023-03087-5

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