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Comparison of gene clustering criteria reveals intrinsic uncertainty in pangenome analyses
BACKGROUND: A key step for comparative genomics is to group open reading frames into functionally and evolutionarily meaningful gene clusters. Gene clustering is complicated by intraspecific duplications and horizontal gene transfers that are frequent in prokaryotes. In consequence, gene clustering...
Autores principales: | Manzano-Morales, Saioa, Liu, Yang, González-Bodí, Sara, Huerta-Cepas, Jaime, Iranzo, Jaime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614367/ https://www.ncbi.nlm.nih.gov/pubmed/37904249 http://dx.doi.org/10.1186/s13059-023-03089-3 |
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