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SARS-CoV-2 primed platelets–derived microRNAs enhance NETs formation by extracellular vesicle transmission and TLR7/8 activation

BACKGROUND: Hyperactive neutrophil extracellular traps (NETs) formation plays a key role in the pathogenesis of severe COVID-19. Extracellular vesicles (EVs) are vehicles which carry cellular components for intercellular communication. The association between COVID-19 patients-derived EVs and NETs f...

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Detalles Bibliográficos
Autores principales: Liao, Tsai-Ling, Liu, Hung-Jen, Chen, Der-Yuan, Tang, Kuo-Tung, Chen, Yi-Ming, Liu, Po-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614402/
https://www.ncbi.nlm.nih.gov/pubmed/37904132
http://dx.doi.org/10.1186/s12964-023-01345-4