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Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study

This retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the d...

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Autores principales: Kumagai, Hiroshi, Funayama, Toru, Sato, Kosuke, Noguchi, Hiroshi, Yoshioka, Tomokazu, Koda, Masao, Yamazaki, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614489/
https://www.ncbi.nlm.nih.gov/pubmed/37908955
http://dx.doi.org/10.7759/cureus.46240
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author Kumagai, Hiroshi
Funayama, Toru
Sato, Kosuke
Noguchi, Hiroshi
Yoshioka, Tomokazu
Koda, Masao
Yamazaki, Masashi
author_facet Kumagai, Hiroshi
Funayama, Toru
Sato, Kosuke
Noguchi, Hiroshi
Yoshioka, Tomokazu
Koda, Masao
Yamazaki, Masashi
author_sort Kumagai, Hiroshi
collection PubMed
description This retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences between the artificial bone, Affinos(® )(Kuraray Co., Tokyo, Japan), and autogenous bone. Two years post-surgery, we evaluated computed tomography (CT) multi-planar reconstruction images in the coronal and sagittal planes. One year after surgery, out of the 24 windows, 17 (70.8%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 18 (47.4%) windows transplanted with Affinos(®) showed bone fusion. Two years post-surgery, out of the 24 windows, 19 (79.2%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 30 (79.0%) windows transplanted with Affinos(®) showed bone fusion, and no difference was observed in the fusion rate at two years post-surgery (P = 0.238). In cases using Affinos(®) for transplanted bone, the bone fusion rate increased between one and two years. The rate of bony fusion using Affinos(®) in lateral lumbar interbody fusion (LLIF) cages is at par with that of autologous bone grafts at two years post-surgery. Affinos(®) is a promising candidate for graft material in LLIF surgery.
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spelling pubmed-106144892023-10-31 Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study Kumagai, Hiroshi Funayama, Toru Sato, Kosuke Noguchi, Hiroshi Yoshioka, Tomokazu Koda, Masao Yamazaki, Masashi Cureus Orthopedics This retrospective cohort study aims to examine the potential differences in bone fusion between autologous bone and artificial bone in the lumbar lateral interbody fusion at 2two years post-surgery. The bone fusions performed in 15 cases and at 34 intervertebral levels were compared to assess the differences between the artificial bone, Affinos(® )(Kuraray Co., Tokyo, Japan), and autogenous bone. Two years post-surgery, we evaluated computed tomography (CT) multi-planar reconstruction images in the coronal and sagittal planes. One year after surgery, out of the 24 windows, 17 (70.8%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 18 (47.4%) windows transplanted with Affinos(®) showed bone fusion. Two years post-surgery, out of the 24 windows, 19 (79.2%) windows transplanted with autologous bones showed bone fusion. Additionally, out of the 38 windows, 30 (79.0%) windows transplanted with Affinos(®) showed bone fusion, and no difference was observed in the fusion rate at two years post-surgery (P = 0.238). In cases using Affinos(®) for transplanted bone, the bone fusion rate increased between one and two years. The rate of bony fusion using Affinos(®) in lateral lumbar interbody fusion (LLIF) cages is at par with that of autologous bone grafts at two years post-surgery. Affinos(®) is a promising candidate for graft material in LLIF surgery. Cureus 2023-09-30 /pmc/articles/PMC10614489/ /pubmed/37908955 http://dx.doi.org/10.7759/cureus.46240 Text en Copyright © 2023, Kumagai et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Orthopedics
Kumagai, Hiroshi
Funayama, Toru
Sato, Kosuke
Noguchi, Hiroshi
Yoshioka, Tomokazu
Koda, Masao
Yamazaki, Masashi
Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title_full Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title_fullStr Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title_full_unstemmed Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title_short Comparing Bone Fusion Rates Between Novel Unidirectional Porous Tricalcium Beta-Phosphate and Autologous Bone in Lumbar Lateral Interbody Fusion: A Two-Year Radiographic Outcome Study
title_sort comparing bone fusion rates between novel unidirectional porous tricalcium beta-phosphate and autologous bone in lumbar lateral interbody fusion: a two-year radiographic outcome study
topic Orthopedics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614489/
https://www.ncbi.nlm.nih.gov/pubmed/37908955
http://dx.doi.org/10.7759/cureus.46240
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