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Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study

To characterize COVID-19 epidemiology, numerous population-based studies have been undertaken to model the risk of SARS-CoV-2 infection. Less is known about what may drive the probability to undergo testing. Understanding how much testing is driven by contextual or individual conditions is important...

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Autores principales: Giardiello, Daniele, Melotti, Roberto, Barbieri, Giulia, Gögele, Martin, Weichenberger, Christian X., Foco, Luisa, Bottigliengo, Daniele, Barin, Laura, Lundin, Rebecca, Pramstaller, Peter P., Pattaro, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614704/
https://www.ncbi.nlm.nih.gov/pubmed/36992656
http://dx.doi.org/10.1080/20477724.2023.2191232
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author Giardiello, Daniele
Melotti, Roberto
Barbieri, Giulia
Gögele, Martin
Weichenberger, Christian X.
Foco, Luisa
Bottigliengo, Daniele
Barin, Laura
Lundin, Rebecca
Pramstaller, Peter P.
Pattaro, Cristian
author_facet Giardiello, Daniele
Melotti, Roberto
Barbieri, Giulia
Gögele, Martin
Weichenberger, Christian X.
Foco, Luisa
Bottigliengo, Daniele
Barin, Laura
Lundin, Rebecca
Pramstaller, Peter P.
Pattaro, Cristian
author_sort Giardiello, Daniele
collection PubMed
description To characterize COVID-19 epidemiology, numerous population-based studies have been undertaken to model the risk of SARS-CoV-2 infection. Less is known about what may drive the probability to undergo testing. Understanding how much testing is driven by contextual or individual conditions is important to delineate the role of individual behavior and to shape public health interventions and resource allocation. In the Val Venosta/Vinschgau district (South Tyrol, Italy), we conducted a population-representative longitudinal study on 697 individuals susceptible to first infection who completed 4,512 repeated online questionnaires at four-week intervals between September 2020 and May 2021. Mixed-effects logistic regression models were fitted to investigate associations of self-reported SARS-CoV-2 testing with individual characteristics (social, demographic, and biological) and contextual determinants. Testing was associated with month of reporting, reflecting the timing of both the pandemic intensity and public health interventions, COVID-19-related symptoms (odds ratio, OR:8.26; 95% confidence interval, CI:6.04–11.31), contacts with infected individuals within home (OR:7.47, 95%CI:3.81–14.62) or outside home (OR:9.87, 95%CI:5.78–16.85), and being retired (OR:0.50, 95%CI:0.34–0.73). Symptoms and next within- and outside-home contacts were the leading determinants of swab testing predisposition in the most acute phase of the pandemics. Testing was not associated with age, sex, education, comorbidities, or lifestyle factors. In the study area, contextual determinants reflecting the course of the pandemic were predominant compared to individual sociodemographic characteristics in explaining the SARS-CoV-2 probability of testing. Decision makers should evaluate whether the intended target groups were correctly prioritized by the testing campaign.
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spelling pubmed-106147042023-10-31 Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study Giardiello, Daniele Melotti, Roberto Barbieri, Giulia Gögele, Martin Weichenberger, Christian X. Foco, Luisa Bottigliengo, Daniele Barin, Laura Lundin, Rebecca Pramstaller, Peter P. Pattaro, Cristian Pathog Glob Health Research Article To characterize COVID-19 epidemiology, numerous population-based studies have been undertaken to model the risk of SARS-CoV-2 infection. Less is known about what may drive the probability to undergo testing. Understanding how much testing is driven by contextual or individual conditions is important to delineate the role of individual behavior and to shape public health interventions and resource allocation. In the Val Venosta/Vinschgau district (South Tyrol, Italy), we conducted a population-representative longitudinal study on 697 individuals susceptible to first infection who completed 4,512 repeated online questionnaires at four-week intervals between September 2020 and May 2021. Mixed-effects logistic regression models were fitted to investigate associations of self-reported SARS-CoV-2 testing with individual characteristics (social, demographic, and biological) and contextual determinants. Testing was associated with month of reporting, reflecting the timing of both the pandemic intensity and public health interventions, COVID-19-related symptoms (odds ratio, OR:8.26; 95% confidence interval, CI:6.04–11.31), contacts with infected individuals within home (OR:7.47, 95%CI:3.81–14.62) or outside home (OR:9.87, 95%CI:5.78–16.85), and being retired (OR:0.50, 95%CI:0.34–0.73). Symptoms and next within- and outside-home contacts were the leading determinants of swab testing predisposition in the most acute phase of the pandemics. Testing was not associated with age, sex, education, comorbidities, or lifestyle factors. In the study area, contextual determinants reflecting the course of the pandemic were predominant compared to individual sociodemographic characteristics in explaining the SARS-CoV-2 probability of testing. Decision makers should evaluate whether the intended target groups were correctly prioritized by the testing campaign. Taylor & Francis 2023-03-29 /pmc/articles/PMC10614704/ /pubmed/36992656 http://dx.doi.org/10.1080/20477724.2023.2191232 Text en © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
spellingShingle Research Article
Giardiello, Daniele
Melotti, Roberto
Barbieri, Giulia
Gögele, Martin
Weichenberger, Christian X.
Foco, Luisa
Bottigliengo, Daniele
Barin, Laura
Lundin, Rebecca
Pramstaller, Peter P.
Pattaro, Cristian
Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title_full Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title_fullStr Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title_full_unstemmed Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title_short Determinants of SARS-CoV-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the CHRIS COVID-19 study
title_sort determinants of sars-cov-2 nasopharyngeal testing in a rural community sample susceptible of first infection: the chris covid-19 study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614704/
https://www.ncbi.nlm.nih.gov/pubmed/36992656
http://dx.doi.org/10.1080/20477724.2023.2191232
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