Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies

There is tremendous need for improved prostate cancer (PCa) models. The mouse prostate does not spontaneously form tumors and is anatomically and developmentally different from the human prostate. Engineered mouse models lack the heterogeneity of human cancer and rarely establish metastatic growth....

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Detalles Bibliográficos
Autores principales: Kostlan, Raymond J., Phoenix, John T., Budreika, Audris, Ferrari, Marina G., Khurana, Neetika, Cho, Jae Eun, Juckette, Kristin, McCollum, Brooke L., Moskal, Russell, Mannan, Rahul, Qiao, Yuanyuan, Griend, Donald J. Vander, Chinnaiyan, Arul M., Kregel, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614761/
https://www.ncbi.nlm.nih.gov/pubmed/37904960
http://dx.doi.org/10.1101/2023.10.13.562280

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