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Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling

Integrin-dependent adhesion to the extracellular matrix (ECM) mediates mechanosensing and signaling in response to altered microenvironmental conditions. In order to provide tissue- and organ-specific cues, the ECM is composed of many different proteins that temper the mechanical properties and prov...

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Detalles Bibliográficos
Autores principales: Conway, James R. W., Isomursu, Aleksi, Follain, Gautier, Härmä, Ville, Jou-Ollé, Eva, Pasquier, Nicolas, Välimäki, Eetu P. O., Rantala, Juha K., Ivaska, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614832/
https://www.ncbi.nlm.nih.gov/pubmed/37844244
http://dx.doi.org/10.1073/pnas.2304288120