Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma

Mostrar otras versiones (1)

Almost all Glioblastoma (GBM) are either intrinsically resistant to the chemotherapeutical drug temozolomide (TMZ) or acquire therapy-induced mutations that cause chemoresistance and recurrence. The genome maintenance mechanisms responsible for GBM chemoresistance and hypermutation are unknown. We s...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Xing, An, Jing, Lou, Jitong, Gu, Qisheng, Ding, Weimin, Droby, Gaith, Wang, Yilin, Wang, Chenghao, Gao, Yanzhe, Shelton, Abigail, Satterlee, Andrew Benson, Mann, Breanna Elizabeth, Hsiao, Yun-Chung, Liu, Chih-Wei, Liu, Kun, Hingtgen, Shawn, Wang, Jiguang, Liu, Zhaoliang, Miller, Ryan, Wu, Di, Vaziri, Cyrus, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614844/
https://www.ncbi.nlm.nih.gov/pubmed/37905107
http://dx.doi.org/10.1101/2023.10.16.562506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614844/
https://www.ncbi.nlm.nih.gov/pubmed/37905107
http://dx.doi.org/10.1101/2023.10.16.562506

Ejemplares similares