Functional Tissue Units in the Human Reference Atlas

Functional tissue units (FTUs) form the basic building blocks of organs and are important for understanding and modeling the healthy physiological function of the organ and changes during disease states. In this first comprehensive catalog of FTUs, we document the definition, physical dimensions, va...

Descripción completa

Detalles Bibliográficos
Autores principales: Bidanta, Supriya, Börner, Katy, Herr, Bruce W., Nagy, Marcell, Gustilo, Katherine S., Bajema, Rachel, Maier, Libby, Molontay, Roland, Weber, Griffin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614912/
https://www.ncbi.nlm.nih.gov/pubmed/37905079
http://dx.doi.org/10.1101/2023.10.16.562593
_version_ 1785129119332171776
author Bidanta, Supriya
Börner, Katy
Herr, Bruce W.
Nagy, Marcell
Gustilo, Katherine S.
Bajema, Rachel
Maier, Libby
Molontay, Roland
Weber, Griffin
author_facet Bidanta, Supriya
Börner, Katy
Herr, Bruce W.
Nagy, Marcell
Gustilo, Katherine S.
Bajema, Rachel
Maier, Libby
Molontay, Roland
Weber, Griffin
author_sort Bidanta, Supriya
collection PubMed
description Functional tissue units (FTUs) form the basic building blocks of organs and are important for understanding and modeling the healthy physiological function of the organ and changes during disease states. In this first comprehensive catalog of FTUs, we document the definition, physical dimensions, vasculature, and cellular composition of 22 anatomically correct, nested functional tissue units (FTUs) in 10 healthy human organs. The catalog includes datasets, illustrations, an interactive online FTU explorer, and a large printable poster. All data and code are freely available. This is part of a larger ongoing international effort to construct a Human Reference Atlas (HRA) of all cells in the human body.
format Online
Article
Text
id pubmed-10614912
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cold Spring Harbor Laboratory
record_format MEDLINE/PubMed
spelling pubmed-106149122023-10-31 Functional Tissue Units in the Human Reference Atlas Bidanta, Supriya Börner, Katy Herr, Bruce W. Nagy, Marcell Gustilo, Katherine S. Bajema, Rachel Maier, Libby Molontay, Roland Weber, Griffin bioRxiv Article Functional tissue units (FTUs) form the basic building blocks of organs and are important for understanding and modeling the healthy physiological function of the organ and changes during disease states. In this first comprehensive catalog of FTUs, we document the definition, physical dimensions, vasculature, and cellular composition of 22 anatomically correct, nested functional tissue units (FTUs) in 10 healthy human organs. The catalog includes datasets, illustrations, an interactive online FTU explorer, and a large printable poster. All data and code are freely available. This is part of a larger ongoing international effort to construct a Human Reference Atlas (HRA) of all cells in the human body. Cold Spring Harbor Laboratory 2023-10-26 /pmc/articles/PMC10614912/ /pubmed/37905079 http://dx.doi.org/10.1101/2023.10.16.562593 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Bidanta, Supriya
Börner, Katy
Herr, Bruce W.
Nagy, Marcell
Gustilo, Katherine S.
Bajema, Rachel
Maier, Libby
Molontay, Roland
Weber, Griffin
Functional Tissue Units in the Human Reference Atlas
title Functional Tissue Units in the Human Reference Atlas
title_full Functional Tissue Units in the Human Reference Atlas
title_fullStr Functional Tissue Units in the Human Reference Atlas
title_full_unstemmed Functional Tissue Units in the Human Reference Atlas
title_short Functional Tissue Units in the Human Reference Atlas
title_sort functional tissue units in the human reference atlas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614912/
https://www.ncbi.nlm.nih.gov/pubmed/37905079
http://dx.doi.org/10.1101/2023.10.16.562593
work_keys_str_mv AT bidantasupriya functionaltissueunitsinthehumanreferenceatlas
AT bornerkaty functionaltissueunitsinthehumanreferenceatlas
AT herrbrucew functionaltissueunitsinthehumanreferenceatlas
AT nagymarcell functionaltissueunitsinthehumanreferenceatlas
AT gustilokatherines functionaltissueunitsinthehumanreferenceatlas
AT bajemarachel functionaltissueunitsinthehumanreferenceatlas
AT maierlibby functionaltissueunitsinthehumanreferenceatlas
AT molontayroland functionaltissueunitsinthehumanreferenceatlas
AT webergriffin functionaltissueunitsinthehumanreferenceatlas

Ejemplares similares