Electrophysiological characterisation of iPSC-derived human β-like cells and an SLC30A8 disease model

iPSC-derived human β-like cells (BLC) hold promise for both therapy and disease modelling, but their generation remains challenging and their functional analyses beyond transcriptomic and morphological assessments remain limited. Here, we validate an approach using multicellular and single cell elec...

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Detalles Bibliográficos
Autores principales: Jaffredo, Manon, Krentz, Nicole A. J., Champon, Benoite, Duff, Claire E., Nawaz, Sameena, Beer, Nicola, Honore, Christian, Clark, Anne, Rorsman, Patrik, Lang, Jochen, Gloyn, Anna L., Raoux, Matthieu, Hastoy, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614917/
https://www.ncbi.nlm.nih.gov/pubmed/37905040
http://dx.doi.org/10.1101/2023.10.17.561014

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