Cargando…

ERK1/2 Inhibition Alleviates Noise-Induced Hearing Loss While Tempering Down the Immune Response

Noise-induced hearing loss (NIHL) is a major cause of hearing impairment, yet no FDA-approved drugs exist to prevent it. Targeting the mitogen activated protein kinase (MAPK) cellular pathway has emerged as a promising approach to attenuate NIHL. Tizaterkib is an orally bioavailable, highly specific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lutze, Richard D., Ingersoll, Matthew A., Thotam, Alena, Joseph, Anjali, Fernandes, Joshua, Teitz, Tal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614960/ https://www.ncbi.nlm.nih.gov/pubmed/37905140 http://dx.doi.org/10.1101/2023.10.18.563007

Ejemplares similares

BRAF inhibition protects against hearing loss in mice
por: Ingersoll, Matthew A., et al.
Publicado: (2020)

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss
por: Teitz, Tal, et al.
Publicado: (2018)

Noise-Induced Hearing Loss
por: Natarajan, Nirvikalpa, et al.
Publicado: (2023)

ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss
por: Kurioka, Takaomi, et al.
Publicado: (2015)

Copresence Was Found to Be Related to Some Pupil Measures in Persons With Hearing Loss While They Performed a Speech-in-Noise Task
por: Pielage, Hidde, et al.
Publicado: (2023)

Avenanthramide-C prevents noise- and drug-induced hearing loss while protecting auditory hair cells from oxidative stress
por: Umugire, Alphonse, et al.
Publicado: (2019)

Hearing Loss in Workers Exposed to Toluene and Noise
por: Chang, Shu-Ju, et al.
Publicado: (2006)

Occupational noise-induced hearing loss in India
por: Nandi, Subroto S., et al.
Publicado: (2008)

The Prevention of Noise Induced Hearing Loss in Children
por: Harrison, Robert V.
Publicado: (2012)

Prevalence of noise-induced hearing loss in drivers
por: Lopes, Andréa Cintra, et al.
Publicado: (2012)

Noise-Induced Hearing Loss in the Police Force
por: Win, Kyaw N., et al.
Publicado: (2015)

Call centers and noise-induced hearing loss
por: Beyan, Ayse Coskun, et al.
Publicado: (2016)

Inflammation associated with noise-induced hearing loss
por: Frye, Mitchell D., et al.
Publicado: (2019)

Cellular mechanisms of noise-induced hearing loss
por: Kurabi, Arwa, et al.
Publicado: (2016)

Early detection of noise-induced hearing loss
por: Meng, Zhao-Li, et al.
Publicado: (2022)

Oleuropein Effect on Noise-Induced Hearing Loss
por: Kümüş, Özgür, et al.
Publicado: (2022)

Speech perception in noise in unilateral hearing loss()
por: Mondelli, Maria Fernanda Capoani Garcia, et al.
Publicado: (2015)

The noise spectrum influence on Noise-Induced Hearing Loss prevalence in workers
por: Boger, Marlene Escher, et al.
Publicado: (2015)

The chinchilla animal model for hearing science and noise-induced hearing loss
por: Trevino, Monica, et al.
Publicado: (2019)

Audiologic Characteristics of Hearing and Tinnitus in Occupational Noise-Induced Hearing Loss
por: Jin Kang, Hee, et al.
Publicado: (2021)

Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis
por: Chen, Diyan, et al.
Publicado: (2022)

Evolution of Hearing in Young Adults: Effects of Leisure Noise Exposure, Attitudes, and Beliefs toward Noise, Hearing Loss, and Hearing Protection Devices
por: Degeest, Sofie, et al.
Publicado: (2022)

Hearing loss in workers exposed to carbon disulfide and noise.
por: Chang, Shu-Ju, et al.
Publicado: (2003)

Effects of furosemide on the hearing loss induced by impulse noise
por: Adelman, Cahtia, et al.
Publicado: (2011)

Leupeptin reduces impulse noise induced hearing loss
por: Gavriel, Haim, et al.
Publicado: (2011)

Hearing loss in the elderly: History of occupational noise exposure
por: Meneses-Barriviera, Caroline Luiz, et al.
Publicado: (2013)

Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
por: Shi, Lijuan, et al.
Publicado: (2016)

Prevalence of Tinnitus and Noise-induced Hearing Loss in Dentists
por: Myers, Jamie, et al.
Publicado: (2016)

The Effect of the Cholesterol Levels on Noise-Induced Hearing Loss
por: Demir, Mehmet Gokhan, et al.
Publicado: (2018)

Noise-Induced hearing loss among professional musicians
por: Pouryaghoub, Gholamreza, et al.
Publicado: (2016)

Effect of Electroacupuncture on Noise-Induced Hearing Loss in Rats
por: Chang, Chia-Hao, et al.
Publicado: (2021)

Thoughts on the potential to compensate a hearing loss in noise
por: Schädler, Marc René
Publicado: (2021)

Guidelines for Diagnosing and Quantifying Noise-Induced Hearing Loss
por: Moore, Brian C. J., et al.
Publicado: (2022)

Factors Affecting Sentence-in-Noise Recognition for Normal Hearing Listeners and Listeners with Hearing Loss
por: Hwang, Jung Sun, et al.
Publicado: (2017)

The effects of a hearing education program on recreational noise exposure, attitudes and beliefs toward noise, hearing loss, and hearing protector devices in young adults
por: Keppler, Hannah, et al.
Publicado: (2015)

Speech-in-Noise Test results of compensation claimants for noise induced hearing loss in Korean male workers: Words-in-Noise Test (WIN) and quick-Hearing-in-Noise Test (HINT)
por: Kim, Ji Soo, et al.
Publicado: (2021)

Noise-Induced Hearing Loss in Gerbil: Round Window Assays of Synapse Loss
por: Jeffers, Penelope W. C., et al.
Publicado: (2021)

Prevention of the Evolution of Workers' Hearing Loss from Noise-Induced Hearing Loss in Noisy Environments through a Hearing Conservation Program
por: Fonseca, Vinicius Ribas, et al.
Publicado: (2015)

All Ears: Potential Help for Noise-Induced Hearing Loss
Publicado: (1999)

Current aspects of hearing loss from occupational and leisure noise
por: Plontke, S., et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_g5sbnmeovk3utmf4227ophkm5u