The widely used Ucp1-Cre(Evdr) transgene elicits complex developmental and metabolic phenotypes

Bacterial artificial chromosome transgenic models, including most Cre-recombinases, enable potent interrogation of gene function in vivo but require rigorous validation as limitations emerge. Due to its high relevance to metabolic studies, we performed comprehensive analysis of the Ucp1-Cre(Evdr) li...

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Detalles Bibliográficos
Autores principales: Halurkar, Manasi Suchit, Inoue, Oto, Mukherjee, Rajib, Paese, Christian Louis Bonatto, Duszynski, Molly, Brugmann, Samantha A., Lim, Hee-Woong, Sanchez-Gurmaches, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614962/
https://www.ncbi.nlm.nih.gov/pubmed/37904917
http://dx.doi.org/10.1101/2023.10.20.563165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614962/
https://www.ncbi.nlm.nih.gov/pubmed/37904917
http://dx.doi.org/10.1101/2023.10.20.563165

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