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The widely used Ucp1-Cre(Evdr) transgene elicits complex developmental and metabolic phenotypes
Bacterial artificial chromosome transgenic models, including most Cre-recombinases, enable potent interrogation of gene function in vivo but require rigorous validation as limitations emerge. Due to its high relevance to metabolic studies, we performed comprehensive analysis of the Ucp1-Cre(Evdr) li...
Autores principales: | Halurkar, Manasi Suchit, Inoue, Oto, Mukherjee, Rajib, Paese, Christian Louis Bonatto, Duszynski, Molly, Brugmann, Samantha A., Lim, Hee-Woong, Sanchez-Gurmaches, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614962/ https://www.ncbi.nlm.nih.gov/pubmed/37904917 http://dx.doi.org/10.1101/2023.10.20.563165 |
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