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Ancestry-specific regulatory and disease architectures are likely due to cell-type-specific gene-by-environment interactions
Multi-ancestry genome-wide association studies (GWAS) have highlighted the existence of variants with ancestry-specific effect sizes. Understanding where and why these ancestry-specific effects occur is fundamental to understanding the genetic basis of human diseases and complex traits. Here, we cha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615008/ https://www.ncbi.nlm.nih.gov/pubmed/37905038 http://dx.doi.org/10.1101/2023.10.20.23297214 |