Cargando…

Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022

Bovine diarrhea is a multi-factorial disease and remains one of the biggest health problems in animal husbandry. The endemic trends of the main pathogens responsible for bovine diarrhea in Inner Mongolia have not been analyzed systematically before. Therefore, the purpose of this study was to estima...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Mengyuan, Chen, Kejia, Liu, PingPing, Wang, Xiaodan, Chen, Yexin, Shang, Hewei, Hao, Yanru, Gao, Peiyuan, He, Xiuling, Xu, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615030/
https://www.ncbi.nlm.nih.gov/pubmed/37908414
http://dx.doi.org/10.7717/peerj.16013
_version_ 1785129137252335616
author Xie, Mengyuan
Chen, Kejia
Liu, PingPing
Wang, Xiaodan
Chen, Yexin
Shang, Hewei
Hao, Yanru
Gao, Peiyuan
He, Xiuling
Xu, Xiaojing
author_facet Xie, Mengyuan
Chen, Kejia
Liu, PingPing
Wang, Xiaodan
Chen, Yexin
Shang, Hewei
Hao, Yanru
Gao, Peiyuan
He, Xiuling
Xu, Xiaojing
author_sort Xie, Mengyuan
collection PubMed
description Bovine diarrhea is a multi-factorial disease and remains one of the biggest health problems in animal husbandry. The endemic trends of the main pathogens responsible for bovine diarrhea in Inner Mongolia have not been analyzed systematically before. Therefore, the purpose of this study was to estimate the prevalence of bovine diarrhea pathogens found in the scattered households of Inner Mongolia in China. Additionally, we assessed for differences in the prevalence of infection based on age and region, as well as determined local prevalence rates and the rates of mixed infections. Using a two-stage random sampling strategy, 3,050 serum samples were collected from 72 bovine herds in 11 leagues and cities in Inner Mongolia, and the positive rates of BVDV, BRV, BCoV, K99, and Mycobacterium paratuberculosis (M. paratuberculosis) antibodies in the samples were detected by ELISA to determine the epidemic trends and epidemic differences of the five pathogens in Inner Mongolia. The positive rates of antibodies based on serum samples were: BVDV, 18.79% (95% CI [17.44–20.22]); BRV, 12.39% (95% CI [11.27–13.61]); BCoV, 12.82% (95% CI [11.68–14.05]); K99, 13.80% (95% CI [12.62–15.07]); and M. paratuberculosis, 10.79% (95% CI [9.74–11.94]). The prevalence rates of BRV, BCoV and K99 at 0–2 months were significantly different from that at 2–6 months, 6–18 months and adult cattle (P < 0.05). The prevalence of BVDV and M. paratuberculosis was the highest in adult cattle, which was significantly different from that in other age groups (P < 0.05). Furthermore, obvious regional epidemiological differences among the five diseases were observed. There was a mixed infection of BRV+BCoV in each age stage, the highest mixed infection being BVDV+BRV+K99 at 0–2 months of age. Our results showed that the cattle of scattered households in the Inner Mongolia of China were endemicly infected with several important cattle pathogens. Most of the pathogens studied occurred between 0–2 months of age and were mixed infections, which greatly influences the health of the cattle and leads to economic loss. These findings are of practical significance for the future prevention and control of bovine diarrhea in the Inner Mongolia or other regions of China.
format Online
Article
Text
id pubmed-10615030
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-106150302023-10-31 Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022 Xie, Mengyuan Chen, Kejia Liu, PingPing Wang, Xiaodan Chen, Yexin Shang, Hewei Hao, Yanru Gao, Peiyuan He, Xiuling Xu, Xiaojing PeerJ Microbiology Bovine diarrhea is a multi-factorial disease and remains one of the biggest health problems in animal husbandry. The endemic trends of the main pathogens responsible for bovine diarrhea in Inner Mongolia have not been analyzed systematically before. Therefore, the purpose of this study was to estimate the prevalence of bovine diarrhea pathogens found in the scattered households of Inner Mongolia in China. Additionally, we assessed for differences in the prevalence of infection based on age and region, as well as determined local prevalence rates and the rates of mixed infections. Using a two-stage random sampling strategy, 3,050 serum samples were collected from 72 bovine herds in 11 leagues and cities in Inner Mongolia, and the positive rates of BVDV, BRV, BCoV, K99, and Mycobacterium paratuberculosis (M. paratuberculosis) antibodies in the samples were detected by ELISA to determine the epidemic trends and epidemic differences of the five pathogens in Inner Mongolia. The positive rates of antibodies based on serum samples were: BVDV, 18.79% (95% CI [17.44–20.22]); BRV, 12.39% (95% CI [11.27–13.61]); BCoV, 12.82% (95% CI [11.68–14.05]); K99, 13.80% (95% CI [12.62–15.07]); and M. paratuberculosis, 10.79% (95% CI [9.74–11.94]). The prevalence rates of BRV, BCoV and K99 at 0–2 months were significantly different from that at 2–6 months, 6–18 months and adult cattle (P < 0.05). The prevalence of BVDV and M. paratuberculosis was the highest in adult cattle, which was significantly different from that in other age groups (P < 0.05). Furthermore, obvious regional epidemiological differences among the five diseases were observed. There was a mixed infection of BRV+BCoV in each age stage, the highest mixed infection being BVDV+BRV+K99 at 0–2 months of age. Our results showed that the cattle of scattered households in the Inner Mongolia of China were endemicly infected with several important cattle pathogens. Most of the pathogens studied occurred between 0–2 months of age and were mixed infections, which greatly influences the health of the cattle and leads to economic loss. These findings are of practical significance for the future prevention and control of bovine diarrhea in the Inner Mongolia or other regions of China. PeerJ Inc. 2023-10-27 /pmc/articles/PMC10615030/ /pubmed/37908414 http://dx.doi.org/10.7717/peerj.16013 Text en ©2023 Xie et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Microbiology
Xie, Mengyuan
Chen, Kejia
Liu, PingPing
Wang, Xiaodan
Chen, Yexin
Shang, Hewei
Hao, Yanru
Gao, Peiyuan
He, Xiuling
Xu, Xiaojing
Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title_full Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title_fullStr Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title_full_unstemmed Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title_short Seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in Inner Mongolia, China between 2019 and 2022
title_sort seroprevalence of five diarrhea-related pathogens in bovine herds of scattered households in inner mongolia, china between 2019 and 2022
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615030/
https://www.ncbi.nlm.nih.gov/pubmed/37908414
http://dx.doi.org/10.7717/peerj.16013
work_keys_str_mv AT xiemengyuan seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT chenkejia seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT liupingping seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT wangxiaodan seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT chenyexin seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT shanghewei seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT haoyanru seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT gaopeiyuan seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT hexiuling seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022
AT xuxiaojing seroprevalenceoffivediarrhearelatedpathogensinbovineherdsofscatteredhouseholdsininnermongoliachinabetween2019and2022