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Complement Component 5 (C5) Deficiency Improves Cognitive Outcome After Traumatic Brain Injury and Enhances Treatment Effects of Complement Inhibitors C1-Inh and CR2-Crry in a Mouse Model

A potent effector of innate immunity, the complement system contributes significantly to the pathophysiology of traumatic brain injury (TBI). This study investigated the role of the complement cascade in neurobehavioral outcomes and neuropathology after TBI. Agents acting at different levels of the...

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Detalles Bibliográficos
Autores principales:	Chen, Min, Edwards, Stephen R., Maskey, Dhiraj, Woodruff, Trent M., Tomlinson, Stephen, Reutens, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615070/ https://www.ncbi.nlm.nih.gov/pubmed/37908321 http://dx.doi.org/10.1089/neur.2023.0024

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