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Regulation of the somatotropic axis by MYC-mediated miRNA repression
The transcription factor MYC is overexpressed in many human cancers and has a significant causal role in tumor incidence and progression. In contrast, Myc (+/−) heterozygous mice, which have decreased MYC expression, exhibit a 10–20% increase in lifespan and a decreased incidence or progression of s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615138/ https://www.ncbi.nlm.nih.gov/pubmed/37908640 http://dx.doi.org/10.3389/fcell.2023.1269860 |