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Proteopathy Linked to Exon-Skipping Isoform of RGR-Opsin Contributes to the Pathogenesis of Age-Related Macular Degeneration

PURPOSE: Proteopathy is believed to contribute to age-related macular degeneration (AMD). Much research indicates that AMD begins in the retinal pigment epithelium (RPE), which is associated with formation of extracellular drusen, a clinical hallmark of AMD. Human RPE produces a drusen-associated ab...

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Detalles Bibliográficos
Autores principales:	Ren, Chi, Cui, Haoran, Bao, Xuan, Huang, Lvzhen, He, Shikun, Fong, Henry K. W., Zhao, Mingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Anatomy and Pathology/Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615142/ https://www.ncbi.nlm.nih.gov/pubmed/37883094 http://dx.doi.org/10.1167/iovs.64.13.41

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