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Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity

Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Bla...

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Autores principales: Ha, Nghiem B, Fan, Bo, Seetharaman, Srilakshmi, Kent, Dorothea S, Yao, Frederick, Shui, Amy M, Huang, Chiung‐Yu, Wadhwani, Sharad I., Lai, Jennifer C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615169/
https://www.ncbi.nlm.nih.gov/pubmed/37908292
http://dx.doi.org/10.1002/jgh3.12976
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author Ha, Nghiem B
Fan, Bo
Seetharaman, Srilakshmi
Kent, Dorothea S
Yao, Frederick
Shui, Amy M
Huang, Chiung‐Yu
Wadhwani, Sharad I.
Lai, Jennifer C
author_facet Ha, Nghiem B
Fan, Bo
Seetharaman, Srilakshmi
Kent, Dorothea S
Yao, Frederick
Shui, Amy M
Huang, Chiung‐Yu
Wadhwani, Sharad I.
Lai, Jennifer C
author_sort Ha, Nghiem B
collection PubMed
description Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Black. There was significant variation in SMI by race/ethnicity; median SMI was lowest in Asian and highest in Black patients. There were significant differences of sarcopenia by race/ethnicity using established SMI cutpoints: 48% NHW, 33% HW, 67% Asian, and 37% Black (P = 0.003). Using these cutpoints, SMI was significantly associated with waitlist mortality only in NHW patients but not in other racial/ethnic groups.[Image: see text]
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spelling pubmed-106151692023-10-31 Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity Ha, Nghiem B Fan, Bo Seetharaman, Srilakshmi Kent, Dorothea S Yao, Frederick Shui, Amy M Huang, Chiung‐Yu Wadhwani, Sharad I. Lai, Jennifer C JGH Open Brief Report Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Black. There was significant variation in SMI by race/ethnicity; median SMI was lowest in Asian and highest in Black patients. There were significant differences of sarcopenia by race/ethnicity using established SMI cutpoints: 48% NHW, 33% HW, 67% Asian, and 37% Black (P = 0.003). Using these cutpoints, SMI was significantly associated with waitlist mortality only in NHW patients but not in other racial/ethnic groups.[Image: see text] Wiley Publishing Asia Pty Ltd 2023-09-20 /pmc/articles/PMC10615169/ /pubmed/37908292 http://dx.doi.org/10.1002/jgh3.12976 Text en © 2023 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Brief Report
Ha, Nghiem B
Fan, Bo
Seetharaman, Srilakshmi
Kent, Dorothea S
Yao, Frederick
Shui, Amy M
Huang, Chiung‐Yu
Wadhwani, Sharad I.
Lai, Jennifer C
Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title_full Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title_fullStr Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title_full_unstemmed Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title_short Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
title_sort variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615169/
https://www.ncbi.nlm.nih.gov/pubmed/37908292
http://dx.doi.org/10.1002/jgh3.12976
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