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Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity
Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Bla...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Publishing Asia Pty Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615169/ https://www.ncbi.nlm.nih.gov/pubmed/37908292 http://dx.doi.org/10.1002/jgh3.12976 |
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author | Ha, Nghiem B Fan, Bo Seetharaman, Srilakshmi Kent, Dorothea S Yao, Frederick Shui, Amy M Huang, Chiung‐Yu Wadhwani, Sharad I. Lai, Jennifer C |
author_facet | Ha, Nghiem B Fan, Bo Seetharaman, Srilakshmi Kent, Dorothea S Yao, Frederick Shui, Amy M Huang, Chiung‐Yu Wadhwani, Sharad I. Lai, Jennifer C |
author_sort | Ha, Nghiem B |
collection | PubMed |
description | Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Black. There was significant variation in SMI by race/ethnicity; median SMI was lowest in Asian and highest in Black patients. There were significant differences of sarcopenia by race/ethnicity using established SMI cutpoints: 48% NHW, 33% HW, 67% Asian, and 37% Black (P = 0.003). Using these cutpoints, SMI was significantly associated with waitlist mortality only in NHW patients but not in other racial/ethnic groups.[Image: see text] |
format | Online Article Text |
id | pubmed-10615169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wiley Publishing Asia Pty Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-106151692023-10-31 Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity Ha, Nghiem B Fan, Bo Seetharaman, Srilakshmi Kent, Dorothea S Yao, Frederick Shui, Amy M Huang, Chiung‐Yu Wadhwani, Sharad I. Lai, Jennifer C JGH Open Brief Report Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients, 55% identified themselves as non‐Hispanic White (NHW), 26% Hispanic White (HW), 13% Asian, and 6% Black. There was significant variation in SMI by race/ethnicity; median SMI was lowest in Asian and highest in Black patients. There were significant differences of sarcopenia by race/ethnicity using established SMI cutpoints: 48% NHW, 33% HW, 67% Asian, and 37% Black (P = 0.003). Using these cutpoints, SMI was significantly associated with waitlist mortality only in NHW patients but not in other racial/ethnic groups.[Image: see text] Wiley Publishing Asia Pty Ltd 2023-09-20 /pmc/articles/PMC10615169/ /pubmed/37908292 http://dx.doi.org/10.1002/jgh3.12976 Text en © 2023 The Authors. JGH Open published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Brief Report Ha, Nghiem B Fan, Bo Seetharaman, Srilakshmi Kent, Dorothea S Yao, Frederick Shui, Amy M Huang, Chiung‐Yu Wadhwani, Sharad I. Lai, Jennifer C Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title | Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title_full | Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title_fullStr | Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title_full_unstemmed | Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title_short | Variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
title_sort | variation in skeletal muscle mass among patients with cirrhosis of different self‐identified race/ethnicity |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615169/ https://www.ncbi.nlm.nih.gov/pubmed/37908292 http://dx.doi.org/10.1002/jgh3.12976 |
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