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The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis

Activation of the Wnt pathway lies at the core of many human cancers. Wnt and macropinocytosis are often active in the same processes, and understanding how Wnt signaling and membrane trafficking cooperate should improve our understanding of embryonic development and cancer. Here, we show that a mac...

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Detalles Bibliográficos
Autores principales: Tejeda-Munoz, Nydia, Azbazdar, Yagmur, Monka, Julia, Binder, Grace, Dayrit, Alex, Ayala, Raul, O'Brien, Neil, De Robertis, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615368/
https://www.ncbi.nlm.nih.gov/pubmed/37902809
http://dx.doi.org/10.7554/eLife.89141