Cargando…

The PMA phorbol ester tumor promoter increases canonical Wnt signaling via macropinocytosis

Mostrar otras versiones (1)

Activation of the Wnt pathway lies at the core of many human cancers. Wnt and macropinocytosis are often active in the same processes, and understanding how Wnt signaling and membrane trafficking cooperate should improve our understanding of embryonic development and cancer. Here, we show that a mac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tejeda-Munoz, Nydia, Azbazdar, Yagmur, Monka, Julia, Binder, Grace, Dayrit, Alex, Ayala, Raul, O'Brien, Neil, De Robertis, Edward M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615368/ https://www.ncbi.nlm.nih.gov/pubmed/37902809 http://dx.doi.org/10.7554/eLife.89141

Ejemplares similares

The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2023)

Addition of exogenous diacylglycerol enhances Wnt/β-catenin signaling through stimulation of macropinocytosis
por: Azbazdar, Yagmur, et al.
Publicado: (2023)

Wnt canonical pathway activates macropinocytosis and lysosomal degradation of extracellular proteins
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2019)

Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking
por: Albrecht, Lauren V., et al.
Publicado: (2018)

GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex Machinery
por: Albrecht, Lauren V., et al.
Publicado: (2020)

Neutrophil Activated by the Famous and Potent PMA (Phorbol Myristate Acetate)
por: Damascena, Hylane Luiz, et al.
Publicado: (2022)

Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Differential signaling during macropinocytosis in response to M-CSF and PMA in macrophages
por: Yoshida, Sei, et al.
Publicado: (2015)

Protocol for culturing and imaging of ectodermal cells from Xenopus
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14
por: Yamamoto, Kazuhiro, et al.
Publicado: (2014)

Effects of PMA (PHORBOL-12-MYRISTATE-13-ACETATE) on the Developing Rodent Brain
por: Dzietko, Mark, et al.
Publicado: (2015)

Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments
por: Sezgin, Erdinc, et al.
Publicado: (2017)

Regulation of urokinase receptors in monocytelike U937 cells by phorbol ester phorbol myristate acetate
Publicado: (1989)

Antiallergic Phorbol Ester from the Seeds of Aquilaria malaccensis
por: Korinek, Michal, et al.
Publicado: (2016)

Myristic Acid, A Side Chain of Phorbol Myristate Acetate (PMA), Can Activate Human Polymorphonuclear Leukocytes to Produce Oxygen Radicals More Potently than PMA
por: Tada, Mika, et al.
Publicado: (2009)

Phorbol esters in seed oil of Jatropha curcas L. (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics
por: Fujiki, Hirota, et al.
Publicado: (2017)

Regulation of Wnt Signaling Pathways at the Plasma Membrane and Their Misregulation in Cancer
por: Azbazdar, Yagmur, et al.
Publicado: (2021)

Misregulation of Wnt Signaling Pathways at the Plasma Membrane in Brain and Metabolic Diseases
por: Karabicici, Mustafa, et al.
Publicado: (2021)

Cell surface dynamics of neutrophils stimulated with phorbol esters or retinoids
Publicado: (1987)

THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS
por: Zucker, Marjorie B., et al.
Publicado: (1974)

Regulation of agrin-induced acetylcholine receptor aggregation by Ca++ and phorbol ester
Publicado: (1988)

Phorbol ester degradation in Jatropha seedcake using white rot fungi
por: Bose, Anjali, et al.
Publicado: (2013)

Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C
Publicado: (1992)

Phorbol esters alter cell fate during development of sea urchin embryos
Publicado: (1992)

Phorbol ester modulation of integrin-mediated cell adhesion: a postreceptor event
Publicado: (1989)

Reorganization of alpha-actinin and vinculin induced by a phorbol ester in living cells
Publicado: (1986)

Phorbol ester induces elevated oxidative activity and alkalization in a subset of lysosomes
por: Chen, Chii-Shiarng
Publicado: (2002)

Targeting Membrane Trafficking as a Strategy for Cancer Treatment
por: Tejeda-Muñoz, Nydia, et al.
Publicado: (2022)

Expression and function of SLC38A5, an amino acid-coupled Na(+)/H(+) exchanger, in triple-negative breast cancer and its relevance to macropinocytosis
por: Ramachandran, Sabarish, et al.
Publicado: (2021)

A Label-Free Quantitative Proteomic Analysis of Mouse Neutrophil Extracellular Trap Formation Induced by Streptococcus suis or Phorbol Myristate Acetate (PMA)
por: Wang, Xiaoping, et al.
Publicado: (2018)

Analyzing phorbol ester effects on gap junctional communication: a dramatic inhibition of assembly
Publicado: (1994)

Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages
Publicado: (1985)

Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation
por: Bokaba, Refilwe Philadelphia, et al.
Publicado: (2017)

Mapping of QTLs for Seed Phorbol Esters, a Toxic Chemical in Jatropha curcas (L.)
por: Amkul, Kitiya, et al.
Publicado: (2017)

“Slow” Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA)
por: Zhu, Lei, et al.
Publicado: (2015)

Comparative membrane lipidomics of hepatocellular carcinoma cells reveals diacylglycerol and ceramide as key regulators of Wnt/β‐catenin signaling and tumor growth
por: Azbazdar, Yagmur, et al.
Publicado: (2023)

Wnt3 Is Lipidated at Conserved Cysteine and Serine Residues in Zebrafish Neural Tissue
por: Dhasmana, Divya, et al.
Publicado: (2021)

Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway
por: Colozza, Gabriele, et al.
Publicado: (2020)

Changes in Wnt and TGF-β Signaling Mediate the Development of Regorafenib Resistance in Hepatocellular Carcinoma Cell Line HuH7
por: Karabicici, Mustafa, et al.
Publicado: (2021)

Phorbol ester treatment stimulates tyrosine phosphorylation of a sea urchin egg cortex protein
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_68l0hm2hhv0um1putkvpn2o8jv