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Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress

Accumulating evidence indicates that acetate is increased under energy stress conditions such as those that occur in diabetes mellitus and prolonged starvation. However, how and where acetate is produced and the nature of its biological significance are largely unknown. We observed overproduction of...

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Detalles Bibliográficos
Autores principales: Wang, Jinyang, Wen, Yaxin, Zhao, Wentao, Zhang, Yan, Lin, Furong, Ouyang, Cong, Wang, Huihui, Yao, Lizheng, Ma, Huanhuan, Zhuo, Yue, Huang, Huiying, Shi, Xiulin, Feng, Liubin, Lin, Donghai, Jiang, Bin, Li, Qinxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615369/
https://www.ncbi.nlm.nih.gov/pubmed/37902629
http://dx.doi.org/10.7554/eLife.87419