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Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease

Chronic kidney disease-mineral and bone disorder is a syndrome of mineral and bone metabolism abnormalities caused by chronic kidney disease. Osteoporosis is a systemic metabolic bone disease characterized by low bone mass, disruption of bone microstructure, increased brittleness, and a higher prope...

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Autor principal: Shen, Yingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615537/
https://www.ncbi.nlm.nih.gov/pubmed/37904427
http://dx.doi.org/10.1097/MD.0000000000035811
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author Shen, Yingjing
author_facet Shen, Yingjing
author_sort Shen, Yingjing
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description Chronic kidney disease-mineral and bone disorder is a syndrome of mineral and bone metabolism abnormalities caused by chronic kidney disease. Osteoporosis is a systemic metabolic bone disease characterized by low bone mass, disruption of bone microstructure, increased brittleness, and a higher propensity for fractures. Both of these conditions significantly affect bone metabolism and substantially increase the risk of fractures. Nutritional vitamin D is an essential trace element in the human body and an important fat-soluble vitamin. One crucial physiological role of nutritional vitamin D is to achieve mineral-bone metabolism balance by regulating calcium homeostasis. This review summarized the metabolism of vitamin in normal population and its specificity in chronic kidney disease. Over the years, the understanding and application of vitamin D in patients with chronic renal failure is changing. As people pay more attention to hypercalcemia, vascular calcification, osteoporosis, nutritional vitamin D has come into people’s attention again. More and more studies are discussing how to prescribe vitamin D supplementation in hemodialysis patients.
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spelling pubmed-106155372023-10-31 Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease Shen, Yingjing Medicine (Baltimore) 5200 Chronic kidney disease-mineral and bone disorder is a syndrome of mineral and bone metabolism abnormalities caused by chronic kidney disease. Osteoporosis is a systemic metabolic bone disease characterized by low bone mass, disruption of bone microstructure, increased brittleness, and a higher propensity for fractures. Both of these conditions significantly affect bone metabolism and substantially increase the risk of fractures. Nutritional vitamin D is an essential trace element in the human body and an important fat-soluble vitamin. One crucial physiological role of nutritional vitamin D is to achieve mineral-bone metabolism balance by regulating calcium homeostasis. This review summarized the metabolism of vitamin in normal population and its specificity in chronic kidney disease. Over the years, the understanding and application of vitamin D in patients with chronic renal failure is changing. As people pay more attention to hypercalcemia, vascular calcification, osteoporosis, nutritional vitamin D has come into people’s attention again. More and more studies are discussing how to prescribe vitamin D supplementation in hemodialysis patients. Lippincott Williams & Wilkins 2023-10-27 /pmc/articles/PMC10615537/ /pubmed/37904427 http://dx.doi.org/10.1097/MD.0000000000035811 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5200
Shen, Yingjing
Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title_full Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title_fullStr Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title_full_unstemmed Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title_short Mini review: A reevaluation of nutritional vitamin D in the treatment of chronic kidney disease
title_sort mini review: a reevaluation of nutritional vitamin d in the treatment of chronic kidney disease
topic 5200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615537/
https://www.ncbi.nlm.nih.gov/pubmed/37904427
http://dx.doi.org/10.1097/MD.0000000000035811
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