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Acan downregulation in parvalbumin GABAergic cells reduces spontaneous recovery of fear memories

While persistence of fear memories is essential for survival, a failure to inhibit fear in response to harmless stimuli is a feature of anxiety disorders. Extinction training only temporarily suppresses fear memory recovery in adults, but it is highly effective in juvenile rodents. Maturation of GAB...

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Detalles Bibliográficos
Autores principales: Lavertu-Jolin, Marisol, Chattopadhyaya, Bidisha, Chehrazi, Pegah, Carrier, Denise, Wünnemann, Florian, Leclerc, Séverine, Dumouchel, Félix, Robertson, Derek, Affia, Hicham, Saba, Kamal, Gopal, Vijaya, Patel, Anant Bahadur, Andelfinger, Gregor, Pineyro, Graçiela, Di Cristo, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615765/
https://www.ncbi.nlm.nih.gov/pubmed/37131076
http://dx.doi.org/10.1038/s41380-023-02085-0