Cargando…

RNA alternative splicing impacts the risk for alcohol use disorder

Alcohol use disorder (AUD) is a complex genetic disorder characterized by problems arising from excessive alcohol consumption. Identifying functional genetic variations that contribute to risk for AUD is a major goal. Alternative splicing of RNA mediates the flow of genetic information from DNA to g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Rudong, Reiter, Jill L., Chen, Andy B., Chen, Steven X., Foroud, Tatiana, Edenberg, Howard J., Lai, Dongbing, Liu, Yunlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615768/ https://www.ncbi.nlm.nih.gov/pubmed/37217680 http://dx.doi.org/10.1038/s41380-023-02111-1

Ejemplares similares

Alcohol use disorder is associated with higher risks of Alzheimer's and Parkinson's diseases: A study of US insurance claims data
por: Zhang, Pengyue, et al.
Publicado: (2022)

Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders
por: Rao, Xi, et al.
Publicado: (2019)

Genetic Research: Who Is At Risk for Alcoholism?
por: Foroud, Tatiana, et al.
Publicado: (2010)

Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans
por: Lai, Dongbing, et al.
Publicado: (2022)

Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data
por: Zhou, Ao, et al.
Publicado: (2012)

Prioritizing single-nucleotide variations that potentially regulate alternative splicing
por: Teng, Mingxiang, et al.
Publicado: (2011)

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
por: Kapoor, Manav, et al.
Publicado: (2021)

Bioinformatics detection of modulators controlling splicing factor‐dependent intron retention in the human brain
por: Chen, Steven X., et al.
Publicado: (2022)

38766 Massively Parallel Reporter Assay Reveals Functional Impact of 3™-UTR SNPs Associated with Neurological and Psychiatric Disorders
por: Chen, Andy B., et al.
Publicado: (2021)

Differential Splicing of Skipped Exons Predicts Drug Response in Cancer Cell Lines
por: Simpson, Edward, et al.
Publicado: (2021)

Modulator-Dependent RBPs Changes Alternative Splicing Outcomes in Kidney Cancer
por: Wang, Yang, et al.
Publicado: (2020)

Assessing the Genetic Risk for Alcohol Use Disorders
por: Foroud, Tatiana, et al.
Publicado: (2012)

Standard linkage and association methods identify the mechanism of four susceptibility genes for a simulated complex disease
por: Pankratz, Nathan, et al.
Publicado: (2005)

The collaborative study on the genetics of alcoholism: Genetics
por: Johnson, Emma C., et al.
Publicado: (2023)

Alcoholism and Alternative Splicing of Candidate Genes
por: Sasabe, Toshikazu, et al.
Publicado: (2010)

The Genetics of Alcohol Metabolism: Role of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Variants
por: Edenberg, Howard J.
Publicado: (2007)

Genes Contributing to the Development of Alcoholism: An Overview
por: Edenberg, Howard J.
Publicado: (2012)

The Collaborative Study on the Genetics of Alcoholism: An Update
por: Edenberg, Howard J.
Publicado: (2002)

Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome
por: Wang, Guohua, et al.
Publicado: (2008)

Genetic Strategies to Detect Genes Involved in Alcoholism and Alcohol-Related Traits
por: Dick, Danielle M., et al.
Publicado: (2002)

Opioid Use Disorder and Alternative mRNA Splicing in Reward Circuitry
por: Huggett, Spencer B., et al.
Publicado: (2022)

Defining Alcohol-Related Phenotypes in Humans: The Collaborative Study on the Genetics of Alcoholism
por: Bierut, Laura Jean, et al.
Publicado: (2002)

SpliceInfo: an information repository for mRNA alternative splicing in human genome
por: Huang, Hsien-Da, et al.
Publicado: (2005)

A regulatory variation in OPRK1, the gene encoding the κ-opioid receptor, is associated with alcohol dependence
por: Edenberg, Howard J., et al.
Publicado: (2008)

Roles of alternative splicing in modulating transcriptional regulation
por: Li, Jin, et al.
Publicado: (2017)

Alternative Splice in Alternative Lice
por: Tovar-Corona, Jaime M., et al.
Publicado: (2015)

Genomic risk for post-traumatic stress disorder in families densely affected with alcohol use disorders
por: Saenz de Viteri, Stacey, et al.
Publicado: (2023)

SpliceTools, a suite of downstream RNA splicing analysis tools to investigate mechanisms and impact of alternative splicing
por: Flemington, Erik K, et al.
Publicado: (2023)

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs
por: Zhang, Xiao-Ou, et al.
Publicado: (2016)

regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions
por: Teng, Mingxiang, et al.
Publicado: (2012)

Re-evaluating the impact of alternative RNA splicing on proteomic diversity
por: Manuel, Jeru Manoj, et al.
Publicado: (2023)

The Function of Pre-mRNA Alternative Splicing in Mammal Spermatogenesis
por: Song, Huibin, et al.
Publicado: (2020)

Alternative Splicing of TAF6: Downstream Transcriptome Impacts and Upstream RNA Splice Control Elements
por: Kamtchueng, Catherine, et al.
Publicado: (2014)

Understanding the Effects of Prenatal Alcohol Exposure Using Three Dimensional Facial Imaging
por: Wetherill, Leah, et al.
Publicado: (2011)

Alternative mRNA Splicing: Control by Combination
Publicado: (2005)

Cell-to-cell variability of alternative RNA splicing
por: Waks, Zeev, et al.
Publicado: (2011)

Stochastic principles governing alternative splicing of RNA
por: Hu, Jianfei, et al.
Publicado: (2017)

Alternative mRNA Splicing in the Pathogenesis of Obesity
por: Wong, Chi-Ming, et al.
Publicado: (2018)

Alternative RNA Splicing in the Pathogenesis of Liver Disease
por: Webster, Nicholas J. G.
Publicado: (2017)

Alternative RNA Splicing in Fatty Liver Disease
por: Wu, Panyisha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7kqegi308b73hd6upigquvbtjp