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Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation

An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro...

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Autores principales: Noor, Mariam Abdi, Benhassen, Leila Louise, Kaspersen, Alexander Emil, Weiss, Marc Gjern, Hasenkam, John Michael, Johansen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615915/
https://www.ncbi.nlm.nih.gov/pubmed/37261643
http://dx.doi.org/10.1007/s12265-023-10393-7
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author Noor, Mariam Abdi
Benhassen, Leila Louise
Kaspersen, Alexander Emil
Weiss, Marc Gjern
Hasenkam, John Michael
Johansen, Peter
author_facet Noor, Mariam Abdi
Benhassen, Leila Louise
Kaspersen, Alexander Emil
Weiss, Marc Gjern
Hasenkam, John Michael
Johansen, Peter
author_sort Noor, Mariam Abdi
collection PubMed
description An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-023-10393-7.
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spelling pubmed-106159152023-11-01 Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation Noor, Mariam Abdi Benhassen, Leila Louise Kaspersen, Alexander Emil Weiss, Marc Gjern Hasenkam, John Michael Johansen, Peter J Cardiovasc Transl Res Original Article An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-023-10393-7. Springer US 2023-06-01 2023 /pmc/articles/PMC10615915/ /pubmed/37261643 http://dx.doi.org/10.1007/s12265-023-10393-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Noor, Mariam Abdi
Benhassen, Leila Louise
Kaspersen, Alexander Emil
Weiss, Marc Gjern
Hasenkam, John Michael
Johansen, Peter
Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title_full Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title_fullStr Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title_full_unstemmed Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title_short Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
title_sort novel expansible aortic annuloplasty ring exhibits similar characteristics as the dacron ring—an in vitro evaluation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615915/
https://www.ncbi.nlm.nih.gov/pubmed/37261643
http://dx.doi.org/10.1007/s12265-023-10393-7
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