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Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation
An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615915/ https://www.ncbi.nlm.nih.gov/pubmed/37261643 http://dx.doi.org/10.1007/s12265-023-10393-7 |
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author | Noor, Mariam Abdi Benhassen, Leila Louise Kaspersen, Alexander Emil Weiss, Marc Gjern Hasenkam, John Michael Johansen, Peter |
author_facet | Noor, Mariam Abdi Benhassen, Leila Louise Kaspersen, Alexander Emil Weiss, Marc Gjern Hasenkam, John Michael Johansen, Peter |
author_sort | Noor, Mariam Abdi |
collection | PubMed |
description | An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-023-10393-7. |
format | Online Article Text |
id | pubmed-10615915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-106159152023-11-01 Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation Noor, Mariam Abdi Benhassen, Leila Louise Kaspersen, Alexander Emil Weiss, Marc Gjern Hasenkam, John Michael Johansen, Peter J Cardiovasc Transl Res Original Article An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-023-10393-7. Springer US 2023-06-01 2023 /pmc/articles/PMC10615915/ /pubmed/37261643 http://dx.doi.org/10.1007/s12265-023-10393-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Noor, Mariam Abdi Benhassen, Leila Louise Kaspersen, Alexander Emil Weiss, Marc Gjern Hasenkam, John Michael Johansen, Peter Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title | Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title_full | Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title_fullStr | Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title_full_unstemmed | Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title_short | Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation |
title_sort | novel expansible aortic annuloplasty ring exhibits similar characteristics as the dacron ring—an in vitro evaluation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10615915/ https://www.ncbi.nlm.nih.gov/pubmed/37261643 http://dx.doi.org/10.1007/s12265-023-10393-7 |
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