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Phosphatidylinositolmannoside vaccination induces lipid-specific Th1-responses and partially protects guinea pigs from Mycobacterium tuberculosis challenge

The concept of donor-unrestricted T cells (DURTs) comprises a heterogeneity of lymphoid cells that respond to an abundance of unconventional epitopes in a non-MHC-restricted manner. Vaccinologists strive to harness this so far underexplored branch of the immune system for new vaccines against tuberc...

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Detalles Bibliográficos
Autores principales: Eckhardt, Emmelie, Schinköthe, Jan, Gischke, Marcel, Sehl-Ewert, Julia, Corleis, Björn, Dorhoi, Anca, Teifke, Jens, Albrecht, Dirk, Geluk, Annemieke, Gilleron, Martine, Bastian, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616071/
https://www.ncbi.nlm.nih.gov/pubmed/37903877
http://dx.doi.org/10.1038/s41598-023-45898-3

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