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Remodeling the cellular stress response for enhanced genetic code expansion in mammalian cells

Genetic code expansion (GCE) reprograms the translational machinery to site-specifically incorporate noncanonical amino acids (ncAAs) into a selected protein. The efficiency of GCE in mammalian cells might be compromised by cellular stress responses, among which, the protein kinase R(PKR)-dependent...

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Detalles Bibliográficos
Autores principales:	Sushkin, Mikhail E., Koehler, Christine, Lemke, Edward A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616097/ https://www.ncbi.nlm.nih.gov/pubmed/37903771 http://dx.doi.org/10.1038/s41467-023-42689-2

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