Novel 3-phenylquinazolin-2,4(1H,3H)-diones as dual VEGFR-2/c-Met-TK inhibitors: design, synthesis, and biological evaluation

Multitarget anticancer drugs are more superior than single target drugs regarding patient compliance, drug adverse effects, drug-drug interactions, drug resistance as well as pharmaceutical industry economics. Dysregulation of both VEGFR-2 and c-Met tyrosine kinases (TKs) could result in development...

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Detalles Bibliográficos
Autores principales: Hassan, Abdelfattah, Mosallam, Ahmed M., Ibrahim, Amal O. A., Badr, Mohamed, Abdelmonsef, Aboubakr H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616113/
https://www.ncbi.nlm.nih.gov/pubmed/37903949
http://dx.doi.org/10.1038/s41598-023-45687-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616113/
https://www.ncbi.nlm.nih.gov/pubmed/37903949
http://dx.doi.org/10.1038/s41598-023-45687-y

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