Characterization of the pathogenic α-Synuclein Variant V15A in Parkinson´s disease

Despite being a major component of Lewy bodies and Lewy neurites, pathogenic variants in the gene encoding alpha-Synuclein (α-Syn) are rare. To date, only four missense variants in the SNCA gene, encoding α-Syn have unequivocally been shown to be disease-causing. We here describe a Parkinson´s disea...

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Detalles Bibliográficos
Autores principales: Diaw, Sokhna Haissatou, Borsche, Max, Streubel-Gallasch, Linn, Dulovic-Mahlow, Marija, Hermes, Julia, Lenz, Insa, Seibler, Philip, Klein, Christine, Brüggemann, Norbert, Vos, Melissa, Lohmann, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616187/
https://www.ncbi.nlm.nih.gov/pubmed/37903765
http://dx.doi.org/10.1038/s41531-023-00584-z

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