Hedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4(+) T cells

INTRODUCTION: Ischemia reperfusion injury (IRI) confers worsened outcomes and is an increasing clinical problem in solid organ transplantation. Previously, we identified a “Ptch(Hi)” T-cell subset that selectively received costimulatory signals from endothelial cell-derived Hedgehog (Hh) morphogens...

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Detalles Bibliográficos
Autores principales: Wang, Shaoxun, Song, Guiyu, Barkestani, Mahsa Nouri, Tobiasova, Zuzana, Wang, Qianxun, Jiang, Quan, Lopez, Roberto, Adelekan-Kamara, Yasmin, Fan, Matthew, Pober, Jordan S., Tellides, George, Jane-wit, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616247/
https://www.ncbi.nlm.nih.gov/pubmed/37915586
http://dx.doi.org/10.3389/fimmu.2023.1248027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616247/
https://www.ncbi.nlm.nih.gov/pubmed/37915586
http://dx.doi.org/10.3389/fimmu.2023.1248027

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