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Hedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4(+) T cells
INTRODUCTION: Ischemia reperfusion injury (IRI) confers worsened outcomes and is an increasing clinical problem in solid organ transplantation. Previously, we identified a “Ptch(Hi)” T-cell subset that selectively received costimulatory signals from endothelial cell-derived Hedgehog (Hh) morphogens...
Autores principales: | Wang, Shaoxun, Song, Guiyu, Barkestani, Mahsa Nouri, Tobiasova, Zuzana, Wang, Qianxun, Jiang, Quan, Lopez, Roberto, Adelekan-Kamara, Yasmin, Fan, Matthew, Pober, Jordan S., Tellides, George, Jane-wit, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616247/ https://www.ncbi.nlm.nih.gov/pubmed/37915586 http://dx.doi.org/10.3389/fimmu.2023.1248027 |
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