A multidomain bio-inspired feature extraction and selection model for diabetic retinopathy severity classification: an ensemble learning approach

Diabetes retinopathy (DR) is one of the leading causes of blindness globally. Early detection of this condition is essential for preventing patients' loss of eyesight caused by diabetes mellitus being untreated for an extended period. This paper proposes the design of an augmented bioinspired multidomain feature extraction and selection model for diabetic retinopathy severity estimation using an ensemble learning process. The proposed approach initiates by identifying DR severity levels from retinal images that segment the optical disc, macula, blood vessels, exudates, and hemorrhages using an adaptive thresholding process. Once the images are segmented, multidomain features are extracted from the retinal images, including frequency, entropy, cosine, gabor, and wavelet components. These data were fed into a novel Modified Moth Flame Optimization-based feature selection method that assisted in optimal feature selection. Finally, an ensemble model using various ML (machine learning) algorithms, which included Naive Bayes, K-Nearest Neighbours, Support Vector Machine, Multilayer Perceptron, Random Forests, and Logistic Regression were used to identify the various severity complications of DR. The experiments on different openly accessible data sources have shown that the proposed method outperformed conventional methods and achieved an Accuracy of 96.5% in identifying DR severity levels.