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An autocatalytic multicomponent DNAzyme nanomachine for tumor-specific photothermal therapy sensitization in pancreatic cancer

Multicomponent deoxyribozymes (MNAzymes) have great potential in gene therapy, but their ability to recognize disease tissue and further achieve synergistic gene regulation has rarely been studied. Herein, Arginylglycylaspartic acid (RGD)-modified Distearyl acylphosphatidyl ethanolamine (DSPE)-polye...

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Detalles Bibliográficos
Autores principales: Yan, Jiaqi, Ma, Xiaodong, Liang, Danna, Ran, Meixin, Zheng, Dongdong, Chen, Xiaodong, Zhou, Shichong, Sun, Weijian, Shen, Xian, Zhang, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616286/
https://www.ncbi.nlm.nih.gov/pubmed/37903795
http://dx.doi.org/10.1038/s41467-023-42740-2