Homodimer-mediated phosphorylation of C/EBPα-p42 S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation

CCAAT/enhancer binding protein α (C/EBPα) regulates myeloid differentiation, and its dysregulation contributes to acute myeloid leukaemia (AML) progress. Clarifying its functional implementation mechanism is of great significance for its further clinical application. Here, we show that C/EBPα regula...

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Detalles Bibliográficos
Autores principales: Wang, Dongmei, Sun, Tao, Xia, Yuan, Zhao, Zhe, Sheng, Xue, Li, Shuying, Ma, Yuechan, Li, Mingying, Su, Xiuhua, Zhang, Fan, Li, Peng, Ma, Daoxin, Ye, Jingjing, Lu, Fei, Ji, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616288/
https://www.ncbi.nlm.nih.gov/pubmed/37903757
http://dx.doi.org/10.1038/s41467-023-42650-3

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