MUC1-C integrates aerobic glycolysis with suppression of oxidative phosphorylation in triple-negative breast cancer stem cells

Activation of the MUC1-C protein promotes lineage plasticity, epigenetic reprogramming, and the cancer stem cell (CSC) state. The present studies performed on enriched populations of triple-negative breast cancer (TNBC) CSCs demonstrate that MUC1-C is essential for integrating activation of glycolyt...

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Detalles Bibliográficos
Autores principales: Yamashita, Nami, Withers, Henry, Morimoto, Yoshihiro, Bhattacharya, Atrayee, Haratake, Naoki, Daimon, Tatsuaki, Fushimi, Atsushi, Nakashoji, Ayako, Thorner, Aaron R., Isenhart, Emily, Rosario, Spencer, Long, Mark D., Kufe, Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
https://www.ncbi.nlm.nih.gov/pubmed/37915591
http://dx.doi.org/10.1016/j.isci.2023.108168

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