Cargando…

Comprehensive characterization of patient-derived xenograft models of pediatric leukemia

Patient-derived xenografts (PDX) remain valuable models for understanding the biology and for developing novel therapeutics. To expand current PDX models of childhood leukemia, we have developed new PDX models from Hispanic patients, a subgroup with a poorer overall outcome. Of 117 primary leukemia...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogojina, Anna, Klesse, Laura J., Butler, Erin, Kim, Jiwoong, Zhang, He, Xiao, Xue, Guo, Lei, Zhou, Qinbo, Hartshorne, Taylor, Garcia, Dawn, Weldon, Korri, Holland, Trevor, Bandyopadhyay, Abhik, Prado, Luz Perez, Wang, Shidan, Yang, Donghan M., Langevan, Anne-Marie, Zou, Yi, Grimes, Allison C., Assanasen, Chatchawin, Gidvani-Diaz, Vinod, Zheng, Siyuan, Lai, Zhao, Chen, Yidong, Xie, Yang, Tomlinson, Gail E., Skapek, Stephen X., Kurmasheva, Raushan T., Houghton, Peter J., Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616347/
https://www.ncbi.nlm.nih.gov/pubmed/37915590
http://dx.doi.org/10.1016/j.isci.2023.108171