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Dual targeting of H(2)S synthesizing enzymes; cystathionine β-synthase and cystathionine γ-lyase by miR-939-5p effectively curbs triple negative breast cancer

INTRODUCTION: Hydrogen sulfide (H(2)S) has been recently scrutinized for its critical role in aggravating breast cancer (BC) tumorigenicity. Several cancers aberrantly express H(2)S synthesizing enzymes; Cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE). However, their levels and interd...

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Detalles Bibliográficos
Autores principales: Nafea, Heba, Youness, Rana A., Dawoud, Alyaa, Khater, Nour, Manie, Tamer, Abdel-Kader, Reham, Bourquin, Carole, Szabo, Csaba, Gad, Mohamed Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616356/
https://www.ncbi.nlm.nih.gov/pubmed/37916110
http://dx.doi.org/10.1016/j.heliyon.2023.e21063