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Approach to Pregnancy in Patients With Lupus Nephritis
Active lupus nephritis (LN) in pregnancy is strongly associated with poor maternal and fetal outcomes and, therefore, has implications on the planning, timing, and management. Prepregnancy evaluation is essential for all LN patients with childbearing potential to ensure pregnancies proceed in a safe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616386/ https://www.ncbi.nlm.nih.gov/pubmed/37915962 http://dx.doi.org/10.1016/j.xkme.2023.100724 |
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author | Tan, Benjamin So, Paolo Nikolai Krishnan, Anoushka Carriazo, Sol Bahamonde, Josélyn Reyes Lamech, Tanuj Moses Hassanein, Mohamed Lerma, Edgar Wiegley, Nasim |
author_facet | Tan, Benjamin So, Paolo Nikolai Krishnan, Anoushka Carriazo, Sol Bahamonde, Josélyn Reyes Lamech, Tanuj Moses Hassanein, Mohamed Lerma, Edgar Wiegley, Nasim |
author_sort | Tan, Benjamin |
collection | PubMed |
description | Active lupus nephritis (LN) in pregnancy is strongly associated with poor maternal and fetal outcomes and, therefore, has implications on the planning, timing, and management. Prepregnancy evaluation is essential for all LN patients with childbearing potential to ensure pregnancies proceed in a safe and timely manner. Both maternal and fetal risks are communicated to patient during the evaluation. Stratification into different risk profile groups is then made based on disease activity and organ impairment severity. Patients with LN are generally divided into 3 main groups. Patients with LN who become pregnant receive treatments that are nonteratogenic and optimal for fetal and maternal outcomes. Throughout the pregnancy period, these patients are monitored closely under surveillance by a multidisciplinary team of clinicians. The management of patients with LN in pregnancy can be challenging both diagnostically (distinguishing LN from pre-eclampsia and determining the role and timing of kidney biopsy) and therapeutically (LN flares during pregnancy and managing a newly diagnosed LN during pregnancy). |
format | Online Article Text |
id | pubmed-10616386 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-106163862023-11-01 Approach to Pregnancy in Patients With Lupus Nephritis Tan, Benjamin So, Paolo Nikolai Krishnan, Anoushka Carriazo, Sol Bahamonde, Josélyn Reyes Lamech, Tanuj Moses Hassanein, Mohamed Lerma, Edgar Wiegley, Nasim Kidney Med GlomCon Mini Review Active lupus nephritis (LN) in pregnancy is strongly associated with poor maternal and fetal outcomes and, therefore, has implications on the planning, timing, and management. Prepregnancy evaluation is essential for all LN patients with childbearing potential to ensure pregnancies proceed in a safe and timely manner. Both maternal and fetal risks are communicated to patient during the evaluation. Stratification into different risk profile groups is then made based on disease activity and organ impairment severity. Patients with LN are generally divided into 3 main groups. Patients with LN who become pregnant receive treatments that are nonteratogenic and optimal for fetal and maternal outcomes. Throughout the pregnancy period, these patients are monitored closely under surveillance by a multidisciplinary team of clinicians. The management of patients with LN in pregnancy can be challenging both diagnostically (distinguishing LN from pre-eclampsia and determining the role and timing of kidney biopsy) and therapeutically (LN flares during pregnancy and managing a newly diagnosed LN during pregnancy). Elsevier 2023-09-17 /pmc/articles/PMC10616386/ /pubmed/37915962 http://dx.doi.org/10.1016/j.xkme.2023.100724 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | GlomCon Mini Review Tan, Benjamin So, Paolo Nikolai Krishnan, Anoushka Carriazo, Sol Bahamonde, Josélyn Reyes Lamech, Tanuj Moses Hassanein, Mohamed Lerma, Edgar Wiegley, Nasim Approach to Pregnancy in Patients With Lupus Nephritis |
title | Approach to Pregnancy in Patients With Lupus Nephritis |
title_full | Approach to Pregnancy in Patients With Lupus Nephritis |
title_fullStr | Approach to Pregnancy in Patients With Lupus Nephritis |
title_full_unstemmed | Approach to Pregnancy in Patients With Lupus Nephritis |
title_short | Approach to Pregnancy in Patients With Lupus Nephritis |
title_sort | approach to pregnancy in patients with lupus nephritis |
topic | GlomCon Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616386/ https://www.ncbi.nlm.nih.gov/pubmed/37915962 http://dx.doi.org/10.1016/j.xkme.2023.100724 |
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