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A glucose-mediated antibiotic resistance metabolic flux from glycolysis, the pyruvate cycle, and glutamate metabolism to purine metabolism

INTRODUCTION: Bacterial metabolic environment influences antibiotic killing efficacy. Thus, a full understanding for the metabolic resistance mechanisms is especially important to combat antibiotic-resistant bacteria. METHODS: Isobaric tags for relative and absolute quantification-based proteomics a...

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Detalles Bibliográficos
Autores principales: Xiang, Jiao, Wang, Shi-wen, Tao, Yuan, Ye, Jing-zhou, Liang, Ying, Peng, Xuan-xian, Yang, Li-fen, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616527/
https://www.ncbi.nlm.nih.gov/pubmed/37915850
http://dx.doi.org/10.3389/fmicb.2023.1267729