Cargando…

Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient

Methotrexate (MTX) is a commonly prescribed medication for the treatment of rheumatoid arthritis (RA). Although effective in managing rheumatoid arthritis symptoms, methotrexate can have adverse effects, including mucositis. This study highlights a case of methotrexate-induced mucositis resulting fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrestha, Rujen, Ojha, Shiva K, Jha, Suman Kumar, Jasraj, Ranjit, Fauzdar, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616533/
https://www.ncbi.nlm.nih.gov/pubmed/37915869
http://dx.doi.org/10.7759/cureus.46290
_version_ 1785129418009608192
author Shrestha, Rujen
Ojha, Shiva K
Jha, Suman Kumar
Jasraj, Ranjit
Fauzdar, Abhishek
author_facet Shrestha, Rujen
Ojha, Shiva K
Jha, Suman Kumar
Jasraj, Ranjit
Fauzdar, Abhishek
author_sort Shrestha, Rujen
collection PubMed
description Methotrexate (MTX) is a commonly prescribed medication for the treatment of rheumatoid arthritis (RA). Although effective in managing rheumatoid arthritis symptoms, methotrexate can have adverse effects, including mucositis. This study highlights a case of methotrexate-induced mucositis resulting from a medication error in a patient with rheumatoid arthritis. The 69-year-old patient recently diagnosed with rheumatoid arthritis was receiving methotrexate therapy as a part of his treatment plan. The patient, however, unintentionally ingested an excessive dose of methotrexate because of a communication error that occurred during the medication administration process. He started displaying signs of oral mucositis, characterized by uncomfortable ulcers and oral mucosa inflammation, within a short period. The buccal mucosa, tongue, and gingiva of the patient's oral cavity displayed numerous ulcerative lesions upon examination. Due to the mucositis's severity, it was challenging to eat, speak, and perform regular oral hygiene procedures. The patient described severe discomfort that had a detrimental effect on his general quality of life. This case serves as a reminder of the importance of accurate medication administration and communication in the management of rheumatoid arthritis. Healthcare professionals should ensure proper dosing and monitoring to minimize the risk of medication errors and associated complications. Additionally, patients should be educated about the potential side effects of methotrexate, including mucositis, to enable early recognition and timely intervention. In conclusion, this study emphasizes the occurrence of methotrexate-induced mucositis because of medication administration errors in a patient with rheumatoid arthritis. By increasing awareness of this potential complication, healthcare providers can improve patient safety and enhance the overall management of rheumatoid arthritis treatment.
format Online
Article
Text
id pubmed-10616533
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-106165332023-11-01 Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient Shrestha, Rujen Ojha, Shiva K Jha, Suman Kumar Jasraj, Ranjit Fauzdar, Abhishek Cureus Other Methotrexate (MTX) is a commonly prescribed medication for the treatment of rheumatoid arthritis (RA). Although effective in managing rheumatoid arthritis symptoms, methotrexate can have adverse effects, including mucositis. This study highlights a case of methotrexate-induced mucositis resulting from a medication error in a patient with rheumatoid arthritis. The 69-year-old patient recently diagnosed with rheumatoid arthritis was receiving methotrexate therapy as a part of his treatment plan. The patient, however, unintentionally ingested an excessive dose of methotrexate because of a communication error that occurred during the medication administration process. He started displaying signs of oral mucositis, characterized by uncomfortable ulcers and oral mucosa inflammation, within a short period. The buccal mucosa, tongue, and gingiva of the patient's oral cavity displayed numerous ulcerative lesions upon examination. Due to the mucositis's severity, it was challenging to eat, speak, and perform regular oral hygiene procedures. The patient described severe discomfort that had a detrimental effect on his general quality of life. This case serves as a reminder of the importance of accurate medication administration and communication in the management of rheumatoid arthritis. Healthcare professionals should ensure proper dosing and monitoring to minimize the risk of medication errors and associated complications. Additionally, patients should be educated about the potential side effects of methotrexate, including mucositis, to enable early recognition and timely intervention. In conclusion, this study emphasizes the occurrence of methotrexate-induced mucositis because of medication administration errors in a patient with rheumatoid arthritis. By increasing awareness of this potential complication, healthcare providers can improve patient safety and enhance the overall management of rheumatoid arthritis treatment. Cureus 2023-09-30 /pmc/articles/PMC10616533/ /pubmed/37915869 http://dx.doi.org/10.7759/cureus.46290 Text en Copyright © 2023, Shrestha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Other
Shrestha, Rujen
Ojha, Shiva K
Jha, Suman Kumar
Jasraj, Ranjit
Fauzdar, Abhishek
Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title_full Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title_fullStr Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title_full_unstemmed Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title_short Methotrexate-Induced Mucositis: A Consequence of Medication Error in a Rheumatoid Arthritis Patient
title_sort methotrexate-induced mucositis: a consequence of medication error in a rheumatoid arthritis patient
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616533/
https://www.ncbi.nlm.nih.gov/pubmed/37915869
http://dx.doi.org/10.7759/cureus.46290
work_keys_str_mv AT shrestharujen methotrexateinducedmucositisaconsequenceofmedicationerrorinarheumatoidarthritispatient
AT ojhashivak methotrexateinducedmucositisaconsequenceofmedicationerrorinarheumatoidarthritispatient
AT jhasumankumar methotrexateinducedmucositisaconsequenceofmedicationerrorinarheumatoidarthritispatient
AT jasrajranjit methotrexateinducedmucositisaconsequenceofmedicationerrorinarheumatoidarthritispatient
AT fauzdarabhishek methotrexateinducedmucositisaconsequenceofmedicationerrorinarheumatoidarthritispatient