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Glomus jugulare tumours are rare but present a treatment challenge due to their anatomy, endocrine and cardiovascular effects. Their care requires a multidisciplinary approach. We present the case of a 62year-old female patient who presented with 4-year history of tinnitus, hearing loss and hyperten...

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Autores principales: Cheruiyot, Davies, Maina, Benson M, Komen, Ahmed, Mogere, Edwin, Cheserem, Beverly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616598/
http://dx.doi.org/10.1093/noajnl/vdad121.033
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author Cheruiyot, Davies
Maina, Benson M
Komen, Ahmed
Mogere, Edwin
Cheserem, Beverly
author_facet Cheruiyot, Davies
Maina, Benson M
Komen, Ahmed
Mogere, Edwin
Cheserem, Beverly
author_sort Cheruiyot, Davies
collection PubMed
description Glomus jugulare tumours are rare but present a treatment challenge due to their anatomy, endocrine and cardiovascular effects. Their care requires a multidisciplinary approach. We present the case of a 62year-old female patient who presented with 4-year history of tinnitus, hearing loss and hypertension. Over a period of 2 weeks she decompensated with bulbar dysfunction and rapid cardiovascular instability. MRI demonstrated a 88 cc right jugulotympanicum para-ganglioma with intracranial, extra-axial extension and encasement of cranial nerves VI to XII, and marked mass effect on the brainstem with compression and left displacement of the medulla. The patient also had hydrocephalus. Clinically she had limited physiological reserve. She underwent partial embolization to reduce the hyperdynamic circulation, a total dose of 54Gy in 30 fractions using IMRT technique and ventriculoperitoneal shunt insertion. She had a prolonged critical care stay .However, she progressively improved over a period of six months with the brainstem oedema resolving. Currently, the patient is living independently with normal cardiovascular status. This case demonstrates the benefit of combining endovascular intervention and radiation therapy in the management of glomus tumours.”
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spelling pubmed-106165982023-11-01 OTHER-12 Cheruiyot, Davies Maina, Benson M Komen, Ahmed Mogere, Edwin Cheserem, Beverly Neurooncol Adv Final Category: Other Glomus jugulare tumours are rare but present a treatment challenge due to their anatomy, endocrine and cardiovascular effects. Their care requires a multidisciplinary approach. We present the case of a 62year-old female patient who presented with 4-year history of tinnitus, hearing loss and hypertension. Over a period of 2 weeks she decompensated with bulbar dysfunction and rapid cardiovascular instability. MRI demonstrated a 88 cc right jugulotympanicum para-ganglioma with intracranial, extra-axial extension and encasement of cranial nerves VI to XII, and marked mass effect on the brainstem with compression and left displacement of the medulla. The patient also had hydrocephalus. Clinically she had limited physiological reserve. She underwent partial embolization to reduce the hyperdynamic circulation, a total dose of 54Gy in 30 fractions using IMRT technique and ventriculoperitoneal shunt insertion. She had a prolonged critical care stay .However, she progressively improved over a period of six months with the brainstem oedema resolving. Currently, the patient is living independently with normal cardiovascular status. This case demonstrates the benefit of combining endovascular intervention and radiation therapy in the management of glomus tumours.” Oxford University Press 2023-10-31 /pmc/articles/PMC10616598/ http://dx.doi.org/10.1093/noajnl/vdad121.033 Text en © The Author(s) 2023. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Final Category: Other
Cheruiyot, Davies
Maina, Benson M
Komen, Ahmed
Mogere, Edwin
Cheserem, Beverly
OTHER-12
title OTHER-12
title_full OTHER-12
title_fullStr OTHER-12
title_full_unstemmed OTHER-12
title_short OTHER-12
title_sort other-12
topic Final Category: Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616598/
http://dx.doi.org/10.1093/noajnl/vdad121.033
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